By

• Bikash Medhi, MBBS, MD(AIIMS), MAMS, FIMSA, Associate Professor, Department of Pharmacology, Research Block B, 4th Floor, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India
• Ajay Prakash, MSc (Pharmacology), DPPM, DPMM, Ex. Jr. Demonstrator, Department of Pharmacology, Research Block B, 4th Floor, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India

Learning pharmacology without animal experiment is not practically suitable though various computer assistance learning models are available for teaching experimental pharmacology as an integral part. The postgraduates perform animal experiments to learn and conduct research studies, finally to establish scientific facts and to make their career in the research field. Fundamental principles of pharmacology deal with essential points of pharmacology, animal experimentation methodology, and interpretation of results. Most important is to impart skill to budding pharmacologists, which is an essential area of teaching. In this book, reader could find some of the useful aspects, e.g. number of worked out examples which will help to translate theory into practice. Authors made a sincere attempt to include as much relevant information as possible with illustrated points and suitable examples to make this book comprehensive. Topics covered in this book have been carefully selected based on most of the recent improvised problems as per curriculum designed for pharmacology. We are hopeful that the present book will be helpful for all the postgraduates related to pharmacology, trainees, and research workers during their day-to-day activities including allied health discipline and scientists in industrial drug discovery set-up and CRO. Several simple and newer experimental models have been incorporated which will help the students to engage in drug discovery in future. Besides this, several important points have been discussed in this book, e.g. ethics of animal experimentation, care of animals, preparation of solutions. Established technologies have been used in different experiments including cell culture in drug discovery. Clinical pharmacology and pharmacokinetics are special features of this book. Several clinical pharmacology topics including pharmacokinetics related to various aspects have been incorporated systematically which will provide exposure to pharmacology residents.