by William T. Jackson

Autophagy, Infection, and the ImmuneResponse provides a unified overview of the roles ofcellular autophagy during microbial infection.

Introductory chapters ground the reader by laying outthe autophagic pathway from a cellularperspective, and listing assays available for measuringautophagy. Subsequent chapters address virus interactions withautophagy machinery, the various roles of autophagy parasiticinfection, and interactions of bacteria with the autophagicpathway. Concluding chapters explore the relationships ofautophagy to systemic immune responses, including antigenpresentation, ER stress, and production of IFN-gamma.

Designed as a resource for those interested in initiatingstudies on the relationship between autophagy and infection orimmunity, the book combines practical state-of the arttechnique descriptions with an overview of the wide variety ofknown interactions between pathogens and the autophagicpathway.

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